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primary antibodies against cyclin-dependent kinase 1 (cdk1/cdc2/cdkn1  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc primary antibodies against cyclin-dependent kinase 1 (cdk1/cdc2/cdkn1
    ALS modulates the expression of CDK2, CDC2, <t>cyclin</t> B1, p21 Waf1/Cip1, <t>and</t> <t>p53</t> in U-2 OS and MG-63 cells. Notes: U-2 OS and MG-63 cells were treated with ALS at 0.1, 1, and 5 μM for 24 hours and then subjected to Western blotting assay. ( A ) Representative blots of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 and ( B ) bar graphs showing the relative expression levels of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 in U-2 OS and MG-63 cells. β-actin was used as the internal control. Data are the mean ± SD of three independent experiments. * P <0.05; ** P <0.01; and *** P <0.001 by one-way ANOVA. Abbreviations: ALS, alisertib; SD, standard deviation; ANOVA, analysis of variance; CDK, cyclin-dependent kinase; OS, osteosarcoma.
    Primary Antibodies Against Cyclin Dependent Kinase 1 (Cdk1/Cdc2/Cdkn1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primary antibodies against cyclin-dependent kinase 1 (cdk1/cdc2/cdkn1/product/Cell Signaling Technology Inc
    Average 90 stars, based on 1 article reviews
    primary antibodies against cyclin-dependent kinase 1 (cdk1/cdc2/cdkn1 - by Bioz Stars, 2026-02
    90/100 stars

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    1) Product Images from "Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway"

    Article Title: Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway

    Journal: Drug Design, Development and Therapy

    doi: 10.2147/DDDT.S74197

    ALS modulates the expression of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 in U-2 OS and MG-63 cells. Notes: U-2 OS and MG-63 cells were treated with ALS at 0.1, 1, and 5 μM for 24 hours and then subjected to Western blotting assay. ( A ) Representative blots of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 and ( B ) bar graphs showing the relative expression levels of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 in U-2 OS and MG-63 cells. β-actin was used as the internal control. Data are the mean ± SD of three independent experiments. * P <0.05; ** P <0.01; and *** P <0.001 by one-way ANOVA. Abbreviations: ALS, alisertib; SD, standard deviation; ANOVA, analysis of variance; CDK, cyclin-dependent kinase; OS, osteosarcoma.
    Figure Legend Snippet: ALS modulates the expression of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 in U-2 OS and MG-63 cells. Notes: U-2 OS and MG-63 cells were treated with ALS at 0.1, 1, and 5 μM for 24 hours and then subjected to Western blotting assay. ( A ) Representative blots of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 and ( B ) bar graphs showing the relative expression levels of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 in U-2 OS and MG-63 cells. β-actin was used as the internal control. Data are the mean ± SD of three independent experiments. * P <0.05; ** P <0.01; and *** P <0.001 by one-way ANOVA. Abbreviations: ALS, alisertib; SD, standard deviation; ANOVA, analysis of variance; CDK, cyclin-dependent kinase; OS, osteosarcoma.

    Techniques Used: Expressing, Western Blot, Standard Deviation



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    primary antibodies against cyclin-dependent kinase 1 (cdk1/cdc2/cdkn1  (Cell Signaling Technology Inc)
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    Cell Signaling Technology Inc primary antibodies against cyclin-dependent kinase 1 (cdk1/cdc2/cdkn1
    ALS modulates the expression of CDK2, CDC2, <t>cyclin</t> B1, p21 Waf1/Cip1, <t>and</t> <t>p53</t> in U-2 OS and MG-63 cells. Notes: U-2 OS and MG-63 cells were treated with ALS at 0.1, 1, and 5 μM for 24 hours and then subjected to Western blotting assay. ( A ) Representative blots of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 and ( B ) bar graphs showing the relative expression levels of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 in U-2 OS and MG-63 cells. β-actin was used as the internal control. Data are the mean ± SD of three independent experiments. * P <0.05; ** P <0.01; and *** P <0.001 by one-way ANOVA. Abbreviations: ALS, alisertib; SD, standard deviation; ANOVA, analysis of variance; CDK, cyclin-dependent kinase; OS, osteosarcoma.
    Primary Antibodies Against Cyclin Dependent Kinase 1 (Cdk1/Cdc2/Cdkn1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primary antibodies against cyclin-dependent kinase 1 (cdk1/cdc2/cdkn1/product/Cell Signaling Technology Inc
    Average 90 stars, based on 1 article reviews
    primary antibodies against cyclin-dependent kinase 1 (cdk1/cdc2/cdkn1 - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    primary antibody against cyclin-dependent kinase 1 (cdk1  (Cell Signaling Technology Inc)
    90
    Cell Signaling Technology Inc primary antibody against cyclin-dependent kinase 1 (cdk1
    ALS modulates the expression of CDK2, CDC2, <t>cyclin</t> B1, p21 Waf1/Cip1, <t>and</t> <t>p53</t> in U-2 OS and MG-63 cells. Notes: U-2 OS and MG-63 cells were treated with ALS at 0.1, 1, and 5 μM for 24 hours and then subjected to Western blotting assay. ( A ) Representative blots of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 and ( B ) bar graphs showing the relative expression levels of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 in U-2 OS and MG-63 cells. β-actin was used as the internal control. Data are the mean ± SD of three independent experiments. * P <0.05; ** P <0.01; and *** P <0.001 by one-way ANOVA. Abbreviations: ALS, alisertib; SD, standard deviation; ANOVA, analysis of variance; CDK, cyclin-dependent kinase; OS, osteosarcoma.
    Primary Antibody Against Cyclin Dependent Kinase 1 (Cdk1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primary antibody against cyclin-dependent kinase 1 (cdk1/product/Cell Signaling Technology Inc
    Average 90 stars, based on 1 article reviews
    primary antibody against cyclin-dependent kinase 1 (cdk1 - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    ALS modulates the expression of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 in U-2 OS and MG-63 cells. Notes: U-2 OS and MG-63 cells were treated with ALS at 0.1, 1, and 5 μM for 24 hours and then subjected to Western blotting assay. ( A ) Representative blots of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 and ( B ) bar graphs showing the relative expression levels of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 in U-2 OS and MG-63 cells. β-actin was used as the internal control. Data are the mean ± SD of three independent experiments. * P <0.05; ** P <0.01; and *** P <0.001 by one-way ANOVA. Abbreviations: ALS, alisertib; SD, standard deviation; ANOVA, analysis of variance; CDK, cyclin-dependent kinase; OS, osteosarcoma.

    Journal: Drug Design, Development and Therapy

    Article Title: Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway

    doi: 10.2147/DDDT.S74197

    Figure Lengend Snippet: ALS modulates the expression of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 in U-2 OS and MG-63 cells. Notes: U-2 OS and MG-63 cells were treated with ALS at 0.1, 1, and 5 μM for 24 hours and then subjected to Western blotting assay. ( A ) Representative blots of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 and ( B ) bar graphs showing the relative expression levels of CDK2, CDC2, cyclin B1, p21 Waf1/Cip1, and p53 in U-2 OS and MG-63 cells. β-actin was used as the internal control. Data are the mean ± SD of three independent experiments. * P <0.05; ** P <0.01; and *** P <0.001 by one-way ANOVA. Abbreviations: ALS, alisertib; SD, standard deviation; ANOVA, analysis of variance; CDK, cyclin-dependent kinase; OS, osteosarcoma.

    Article Snippet: Primary antibodies against human p53, p21 Waf1/Cip1, cyclin B1, cyclin-dependent kinase 1 (CDK1/CDC2/CDKN1), CDK2, PUMA, Bax, Bcl-2, cytochrome c, cleave caspase-3 and 9, beclin 1, Sirt1, nuclear factor-erythroid-2-related factor 2 (Nrf2), microtubule-associated protein 1A/1B-light chain 3 (LC3-I), LC3-II, phosphatase and tensin homolog (PTEN) PI3K, phosphorylated PI3K (p-PI3K/p85 at Tyr458), AMPK, p-AMPK at Thr172, p38 mitogen-activated protein kinase (MAPK), p-p38 MAPK at Thr180/Tyr182, Akt, p-Akt at Ser473, mTOR, p-mTOR at Ser2448, and EMT antibody sampler kit (No: #9782) were all purchased from Cell Signaling Technology Inc. (Beverly, MA, USA).

    Techniques: Expressing, Western Blot, Standard Deviation